Previous studies identified HNF1A‐AS1 as a functional lncRNA—HNF1A‐AS1 was significantly up‐regulated in oesophageal adenocarcinoma and lung adenocarcinoma tissues; increased HNF1A‐AS1 expression could regulate cell proliferation and metastasis in lung adenocarcinoma 18, while knockdown of HNF1A‐AS1 significantly inhibited cell proliferation, migration and invasion in oesophageal adenocarcinoma 19. This evidence concerns the gene HNF1A and lung adenocarcinoma.