The results were completely in concordance with the simple RT-PCR approach, i.e. ODF4, MAGEA3, and MAGEB4 mRNA were detected in 40 (54.8%), 46 (63%), and 39 (53.4%) TCC patients and 15 (26.3%), 8 (14%), and 3 (5.3%) non-TCC individuals, respectively. The gene discussed is ODF4; the disease is tarsal-carpal coalition syndrome.