Expression of high-risk HPV E6 and E7 in HPV-negative C33A cervical carcinoma cells and primary human epithelial cells causes increased expression of DROSHA and DICER [164], and many DROSHA-regulated miRNAs are dysregulated in high-risk HPV16 E6/E7 expressing cells [155,164]. The gene discussed is DROSHA; the disease is cervical carcinoma.