In our own study, pre-treating C57BL/6 mice with the ITC sulforaphane for seven days ameliorated a DSS-induced colitis phenotype which has been approved by an amendment of the disease activity index, the colon length, the appearance of the intestinal mucosa assessed by colonoscopy, the histopathology and the expression levels of pro-inflammatory markers and Nrf2-regulated cytoprotective enzymes [95]. Here, NFE2L2 is linked to colitis.