Despite this, we noted that the list of WS-DMPs included three CpG sites (cg27111250, cg10129063 and cg27639662) mapping in the S_Shore of the chr4:81109887-81110460 CpG island in the PR domain containing eight (PRDM8) genes and hypermethylated in WS patients compared to CTRs. The gene discussed is PRDM8; the disease is Werner syndrome.