NGF and diabetes mellitus: Comparably, in an adapted murine model of autoimmune diabetes, we have shown that a transfer of antigen-loaded and CpG-stimulated pDCs treated with NGF led to an alleviated clinical phenotype in heterozygous RIP-CD80GP mice characterized by reduced glucose levels and delayed onset of diabetes compared with pDCs stimulated with CpG alone (Figure 3) (26).