Pernicious anemia correlated with seven reactivities, including gastrointestinal factor GIF that is an established autoantigen in pernicious anemia patients (35); five specificities, including GAD1 and GAD2, correlated with vitiligo; and autoantibodies to GABPB2 correlated with autoimmune hepatitis in APECED patients. This evidence concerns the gene GAD2 and pernicious anemia.