NFIA and early-onset autosomal dominant Alzheimer disease: In addition, a report showed that the serum miR-223 might be a potential biomarker for Alzheimer’s disease evaluation59, and another study represented that miR-223/nuclear factor I-A axis could regulate glial precursor proliferation and tumorigenesis in the central nervous system60, indicating that miR-223 might play critical roles in neurological diseases.