However, some studies have shown that PD-L1 positivity was more frequent in EGFR wild-type28, 44, 46, and other studies have shown no association between PD-L1 expression and EGFR mutations23, 26, 27.The present meta-analysis investigated the correlation of PD-L1 expression with EGFR mutations in lung cancers. The gene discussed is EGFR; the disease is lung cancer.