Using data from 28 patients and 20 healthy controls, Kolundžić et al. identified association signals of rs1800470 in TGFB1 and rs1800796 in IL-6 with severe hip osteoarthritis in adulthood20, and using data from 68 cases and 152 controls, Čengić et al. reported significant associations between these two SNPs and severe hip osteoarthritis21. This evidence concerns the gene IL6 and osteoarthritis, hip.