Although the fasting immunoreactive insulin concentration (f-IRI) and homeostatic model assessment of insulin resistance [HOMA-IR] were significantly higher in patients with NAFLD than in those with C-CH, other parameters of glucose intolerance (glycated haemoglobin [HbA1c], and 1,5-anhydroglucitol[1,5-AG]) were not significantly different between the two groups. This evidence concerns the gene INS and Insulin resistance.