BCL2 and cancer: ATF5 also promotes survival of malignant cells by stimulating expression of anti-apoptotic B-cell leukemia-2 (BCL2) and myeloid cell leukemia sequence-1 (MCL1), a BCL2 family member (Sheng et al. 2010; Dluzen et al. 2011), indicating a prosurvival role in cancer.