Otherwise, previously, a novel resistance relative gene, tongue cancer resistance-associated protein 1 (TCRP1) was cloned by our lab from the tongue cancer multi-drug resistance cell line Tca8113/Pingyangmycin (Tca8113/PYM), which mediated a specific resistance to cDDP part due to activation of the PI3K/Akt/NF-κB signaling pathway [16–19]. This evidence concerns the gene FAM168A and tongue cancer.