When only the saliva biomarkers were taken into consideration, a 3-marker model comprising of salivary G-CSF, TNF-α and VEGF diagnosed TB disease in the training sample set (n = 54; n = 27 TB and n = 27 ORD) with a sensitivity of 63% (17/27) and a specificity of 63% (17/27). Here, TNF is linked to tuberculosis.