Except for IFN-γ (p value 0.04) in saliva (Table 7, Fig. 4), serum levels of IL-6 and VEGF were significantly different between the active TB patients and latent TB infection or uninfected (No TB individuals) with p-values ranging between <0.0001 to 0.01 and area under the ROC curve ranging between 071 and 0.86 (Table 7, Figs. 4, 5). Here, IL6 is linked to tuberculosis.