The relative protein expression of HER2 (siRNA1: 36.8±0.5%; siRNA2: 59.4±0.7%; control: 100±1.2%), AKT (siRNA1: 17.3±0.5%; siRNA2: 47.9±0.9%; control: 100±1.0%), and p-AKT (siRNA1: 13.7±0.2%; siRNA2: 68.7±1.4%; control: 100±1.2%) to β-actin in breast ductal carcinoma cells decreased after C35 protein was interfered by siRNA1 and siRNA2, compared with the control group (p < 0.05, Fig 6A and 6B). The gene discussed is AKT1; the disease is breast ductal adenocarcinoma.