In addition, the migration of breast ductal carcinoma cells decreased when C35 protein was interfered by siRNA1 for 24 h (migration index: 0.6±0.1 versus 1.0±0.1; p < 0.05, Fig 3), and for 48 h (migration index: 0.3±0.1 versus 1.0±0.1; p < 0.05, Fig 3). This evidence concerns the gene MIEN1 and breast ductal adenocarcinoma.