Levels of fractalkine were also increased in cell supernatants obtained 24hrs following RV16 or RV1B infection compared to non-infected PBMCs in asthmatics (n = 15) (Fig 3B, P<0.001 for both), however this increase was not statistically significant for non-asthmatic subjects (Fig 3A). The gene discussed is CX3CL1; the disease is infection.