In this study, serum obestatin levels in patients with AP were elevated at admission, but were not correlated with AP severity; these findings are consistent with those of Kanat et al.[18] Unlike serum ghrelin levels, serum obestatin levels differed significantly between patients with AP caused by hypertriglyceridemia and those with AP of other etiologies. The gene discussed is GHRL; the disease is hypertriglyceridemia.