Interestingly, knockdown of H2A.Z.1, but not H2A.Z.2, led to altered expression of several candidate genes linked to psychiatric disorders such as autism and schizophrenia (Neurexin1, Shank3, CaMK2G, Vamp7, Gsk3b, Tuba8, Grm8, etc.). Here, GSK3B is linked to schizophrenia.