Schutz and colleagues [8] have previously reported an IgA and IgM response in all healthy individuals vaccinated with Pneumovax (8/10 PCP IgA>150 U/mL, with the 2/10<150 U/mL possessing a >5 fold increase in concentration post-vaccination, and 10/10 PCP IgM>20 U/mL). This evidence concerns the gene CD40LG and pneumocystosis.