We have in the past identified 2 novel M. tuberculosis thymidylate kinase (TMKmt) epitopes whose capability to designate TB exposure status among a largely HIV −ve cohort by host-specific antibody (Ab: IgM and IgG) detecting enzyme immuno-assays (EIA) was reported (unpublished data) [22,23]. The gene discussed is DTYMK; the disease is tuberculosis.