Analyzing the relationship of Sorcin expression with clinicopathologic features showed that high Sorcin expression significantly correlated with aggressive clinicopathological variables such as multiple nodules (P = 0.001; Table 1), larger tumor size (P < 0.001; Table 1), microvascular invasion (P < 0.001; Table 1), higher Edmondson-Stainer grade (P = 0.002; Table 1), and advanced TNM (P < 0.001; Table 1) or BCLC stage (P < 0.001; Table 1). Here, SRI is linked to neoplasm.