SRI and hepatocellular carcinoma: To investigate the role of Sorcin in the metastasis of HCC, we overexpressed Sorcin in HepG2 cells (Supplementary Fig. 4A1) and stably knocked down Sorcin in HCCLM3 (Supplementary Fig. 4B2) according to the expression level of Sorcin in HCC cell lines and biological characteristics of HCC cell lines16, 17.