Lineage associated transcription factors include MITF for the melanoma cell line SK-MEL-5 [42], TP63 for the lung cancer line A549 [43], KLF5 for the colon cancer line HT-29 [44], and ETS family transcription factors for prostate, colon, ovarian, and breast cancer cell lines [45–49]. The gene discussed is KLF5; the disease is melanoma.