According to the international diabetes federation, the metabolic syndrome (MetS) is characterised by at least three of five clinical findings: central obesity, elevated blood pressure (systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥85 mmHg), elevated serum triglycerides (≥150 mg dL−1), low serum high-density lipoprotein (HDL) (<40 mg dL−1in males and <50 mg dL−1 in females), and insulin resistance (fasting plasma glucose ≥100 mg dL−1) [1]. Here, INS is linked to metabolic syndrome.