This gene set includes numerous cytokines that mediate Th2 cell signaling associated with asthma (IL3, IL4, IL5, IL9, IL10 and IL13), as well as components of the IgE receptor (FCERA, FCERG, MS4A2) and eosinophil granule proteins (ECP, EDN, EPX, and MBP). The gene discussed is MS4A2; the disease is asthma.