In this study, we focused on the zinc transporter ZIP13 because Zip13-deficient (Zip13-KO) mice and humans with spondylocheirodysplastic Ehlers-Danlos syndrome who carry a loss-of-function mutation in SLC39A13 have been reported to have a significantly decreased white fat mass [23]. The gene discussed is SLC39A13; the disease is Ehlers-Danlos syndrome.