To validate methylation changes in the promoters of SOX10 and FOXG1 in brainstem and thalamic gliomas, three other data sets, methylation data of 32 thalamic gliomas, 26 brainstem gliomas, and 46 cerebral gliomas obtained from previous reports, were combined and analyzed with our data (Fig. 6d) [2, 14, 55]. Here, FOXG1 is linked to brain stem glioma.