VEGFA and diabetes mellitus: Aside from enhancing cellular glucose uptake and promoting the reorganisation of F-actin structures, podocyte IR signalling has the capacity to regulate vascular endothelial growth factor (VEGF)-A production [56], cell viability [20], reactive oxygen species (ROS) production and autophagy [57], all of which are key in maintaining glomerular filtration and are dysregulated in diabetes.