In conclusion, the NF-κB pathway functions as a molecular link between inflammation and tumorigenesis due to its ability to stimulate the expression of proinflammatory cytokines, antiapoptotic genes, angiogenesis factors, and proteases, which promote tumor initiation and ensure the survival and proliferation as well as invasion of malignant cells (Figure 1). This evidence concerns the gene NFKB1 and neoplasm.