Such expression changes were evident, particularly in the late myopia dataset where a wide range of genes linked with oxidative stress were either up-regulated (GPX1, GSTA3, MT-4, APOA1, OTUB, PTGDS, HSPB1, HSPB2) or down-regulated (XHD, SLC40A1, TF, SOD3, HPGDS, BCMO1). The gene discussed is MT4; the disease is myopia.