Among genes with significantly increased expression in the CD271high subsets were mediators of tumor cell migration e.g. AXL30 and members of the lysyl-oxidase family LOX26 and LOXL231 as well as the less characterized SERTAD4 (SERTA Domain-Containing Protein 4), (SI, Figure S6D-E). The gene discussed is SERTAD4; the disease is neoplasm.