In contrast in early observations of the Sardinian population where beta-thalassaemia and G6PD deficiency co-exist, it was noted that subjects with G6PD deficiency and concomitant beta-thalassaemic trait were less likely to have favism as compared to G6PD deficient subjects with a normal haemoglobin type22, 23. Here, G6PD is linked to G6PD deficiency.