Interestingly, genes involved in B-cell development such as BCL6 (B-Cell CLL/Lymphoma 6; FC = 8.3) and BTK (Bruton Agammaglobulinemia Tyrosine Kinase; FC = 3.4) as well as T-cell activation including LCP (Lymphocyte Cytosolic Protein 1; FC = 7.4) and FYB (FYN Binding Protein; FC = 8.2) were upregulated. Here, KLHDC2 is linked to B-cell chronic lymphocytic leukemia.