The median IL-6 level was 9.04 pg/ml (mean: 35.9 pg/ml, range: 0–552.6 pg/ml) in patients with STS and 3.31 pg/ml (range = 0–13.5 pg/ml, mean = 3.89 pg/ml) in patients with benign soft tissue tumors. This evidence concerns the gene IL6 and benign soft tissue neoplasm.