As shown in Fig. 2, AML patients with higher PIM-1 expression had significant correlation with DFS (P = 0.0158), RR (P = 0.0219) and OS (P = 0.0015) compared to those with lower PIM-1 expression and no significant difference in EFS (Additional file 2: Table S1). This evidence concerns the gene PIM1 and acute myeloid leukemia.