Immunohistochemical analysis has revealed higher TRIM28 levels in significant proportions of breast, lung, liver, gastric, and prostate tumors (Fig. 3; for more information see TRIM28 at www.proteinatlas.org), suggesting that TRIM28 upregulation is a common feature of many epithelial cancers [16–21, 23–26]. Here, TRIM28 is linked to prostate neoplasm.