It is therefore of particular note that many of the CSF findings from patients with pattern II lesions were more similar to what has been reported in AQP4-IgG-positive NMO [43, 48, 49] and MOG-IgG-positive EM [17, 34–36] than to what was found in patients with pattern I lesions in our study (Tables 1, 2, 3, 4, 5, 6, 7, and 8). Here, AQP4 is linked to neuromyelitis optica.