With suspicious prostatic imaging findings, the corresponding prostate cancer detection rates for the groups with PSA levels of less than 4.0, 4.0 to 10.0, 10.0 to 20.0, 20.0 to 100.0, and ≥ 100.0 ng/ml were 66.7, 48.2, 52.3, 61.3, and 100%, respectively (Table 3). This evidence concerns the gene KLK3 and Familial prostate cancer.