Nilsson et al. [127] found that urinary exosomes in patients with prostate cancer expressed β-catenin, prostate cancer gene-3 (PCA-3), transmembrane serine protease 2-ETS transcription factor family member-related gene fusion (TMPRSS2 -ERG) and other prostate cancer-related markers. Here, TMPRSS2 is linked to Familial prostate cancer.