CD24 can also be found in the cytoplasm inside MVBs and released into the extracellular environment via exosomes, in which case it is correlated with more aggressive forms of ovarian carcinoma, worsening the prognoses and therefore, shortening patients’ survival times [128].In the exosomes isolated from sera of ovarian cancer patients, Li et al. [97] found that epithelial ovarian cancer markers (such as Claudin 4) gradually increased with the development of cancer. This evidence concerns the gene CLDN4 and ovarian cancer.