Indeed, although the vast majority of studies have been focused on the role played by androgens on PCa development/progression and their therapeutic implications [5, 6], other endocrine systems have been also associated with PCa tumorigenesis, including estrogens, LH/FSH, IGF-I, somatostatin, etc. [7, 8]. The gene discussed is BRD2; the disease is posterior cortical atrophy.