Herein, we have expanded those results by demonstrating that In1-ghrelin mRNA levels are overexpressed in a battery of PCa biopsies from patients diagnosed with high-risk PCa, compared to NP samples, which is consistent with previous results indicating that In1-ghrelin overexpression is a common hallmark shared by other endocrine-related tumors such as breast-cancer, pituitary-tumors and NETs [20, 22, 23]. Here, GHRL is linked to breast cancer.