Analysis of the ghrelin-system in PCa biopsies from a cohort (Table 1) of high-risk patients (n = 52) compared to normal prostate (NP) control samples (n = 12), revealed that native-ghrelin and In1-ghrelin mRNA was detected in 83,3 and 66,6% of control-patients and in 90 and 88,5% of PCa samples, respectively (Table 1). This evidence concerns the gene GHRL and posterior cortical atrophy.