Around 19.1% of the colonoscopies saved upon increasing the f-Hb cut-off to 25 μg Hb/g faeces will have an AN, and this percentage rises to 24.4% on increasing the f-Hb cut-off to 60 μg Hb/g faeces It can also be seen that the CRC missed were diagnosed mostly at an early stage (Stage I-II: from 70.2% in men to 66.3% in women). This evidence concerns the gene GSTM1 and colorectal carcinoma.