We observed a higher PPV for AN and higher detection rates for CRC and AN than other programmes, these results could be due to the high rate of compliance to colonoscopy assessment, that allowed a minimal loss of neoplasm detection As reported in recently published studies [26, 37], higher positivity was found in men at the full range of f-Hb cut-offs. Here, GSTM1 is linked to colorectal carcinoma.