VDR and liver dysplastic nodule: The search yielded 67 articles, 7 studies [18, 22–27] contain 1230 DN patients and 1334 diabetic controls were finally recruited into our meta-analysis according to the inclusion and exclusion criteria, all studies reporting the association among ApaI, BsmI, FokI, TaqI of VDR gene polymorphisms and DN susceptibility (Fig. 1).