Pro‐inflammatory cytokines play a predominant role during disc degeneration by inducing catabolic proteases, which drive extracellular matrix degeneration.6, 7 We previously showed that IL‐1α induces the expression of IL‐6 and catabolic protease levels in nucleus pulpous cells in 3D culture, and PEMF treatment inhibited this upregulation induced by IL‐1α after 4 days culture.35 These data suggested that PEMF can repress inflammatory responses that play a causal role in musculoskeletal tissue degeneration. Here, IL1A is linked to intervertebral disk degenerative disorder.