DAGLB and post-traumatic stress disorder: Previous research has demonstrated that reduced 2-AG levels are associated with increased risk of outcomes such as post-traumatic stress disorder and major depression,52, 53, 54 while animal studies have demonstrated that increases in 2-AG through pharmacological intervention may reduce anxiety-like behaviours.55, 56 Given the role of DAGLB in the synthesis of 2-AG, it is therefore of great interest that increases in DAGLB expression corresponded with greater reductions in severity, while decreases in DAGLB expression corresponded with lower reductions in severity.