Among Xp11 tRCCs, Xp11 tRCC with an ASPSCR1-TFE3 fusion, which is also detected in alveolar soft part sarcoma, was reported to have a worse prognosis than Xp11 tRCCs with other fusion partners [34]. Here, ASPSCR1 is linked to renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions.