Finally, while most evidence reflects an important role of CCL5 and the eotaxins in asthma, some studies reported that there was no increase in CCL5 or eotaxin expression in BAL, airway epithelium brushings, or bronchial biopsies between asthmatics and healthy controls (92, 103, 121, 128, 129). This evidence concerns the gene CCL5 and asthma.