P2RY12 and asthma: Anti-platelet drugs (e.g., aspirin, P2Y12 antagonists clopidogrel, and prasugrel) used in the prevention of thrombi in patients with cardiovascular disease have not been extensively tested in non-thrombotic diseases, and especially asthma, although prasugrel was reported to have a limited (if any) beneficial effect in patients with asthma (95).