MYD88 and infection: These results of the present study are consistent with, and explain mechanistically the reduced phagocytosis and enhanced P. gingivalis survival in Myd88−/− mice (as compared to WT mice) in the subcutaneous chamber infection model where neutrophils and macrophages constitute the vast majority of cells responding to challenge (Burns et al., 2010; Steinmetz et al., 2016).