The results in Figure 8E revealed that inoculation with WT for 2 h significantly increased the expressions of LC3-II, Beclin 1, Caspase-1 and mature IL-1β as well as the phosphorylation of JNK and NF-κB in mice, which were prevented by infection with the VvpM mutant. The gene discussed is NFKB1; the disease is infection.