sOP children did not show a higher mucosal IgG (Figure 4A) or IgA (Figure 4B) to any of the four Mcat proteins at Mcat NP colonization compared to those at onset of AOM except a higher mucosal IgG to Hag5–9 upon Mcat NP colonization than that at onset of AOM (P = 0.015, Figure 4A). The gene discussed is MCAT; the disease is infectious otitis media.