IFNB1 and infection: Therefore, we aimed to investigate the levels of IFN-β, IFN-γ, and IL-10 before (day 0) and after (day 2) the infection with S. pneumoniae as indicated in the experimental protocol of Figure 5A. The three cytokines were increased in HK1505 and PG1505 groups indicating that their elevated levels persisted up to 5 days of the last poly(I:C) administration (Figure 6A).